Latest Publications (IPM affiliated researchers Bold):

Lausten-Thomsen U, Gamborg M, Bøjsøe C, Hedley PL, Hagen CM, Christiansen M, Holm JC. Longitudinal changes in C-reactive protein, proform of eosinophil major basic protein, and pregnancy-associated plasma protein-A during weight changes in obese children. J Pediatr Endocrinol Metab. 2015;28:393-398.

Summaries:
A group of obese children was followed through a 3 month weight loss program, and a through 2 year follow up, where the children gained weight. Three risk factors for heart disease where measured throughout the study, and we found that hs-CRP levels followed the changing levels of obesity, whereas PAPP-A and Pro-MBP showed much higher stability. These results suggest that PAPP-A and Pro-MBP are potential early risk markers for heart disease.  

En gruppe svært overvægtige børn blev fulgt gennem et 3 måneders vægttabsforløb og et 2 årigt opfølgningsforløb, hvor børnene tog på igen. Tre risiko faktorer for hjerte sygdom blev målt igennem hele forløbet. Vi fandt at hs-CRP niveauerne fulgte børnenes vægt ned og op igen, mens PAPP-A og Pro-MBP var meget mere stabile. Disse resultater viser, at PAPP-A og Pro-MBP måske kan bruges som tidlige risiko markører for hjertesygdom.

Most SW, Højgaard B, Teilmann G, Andersen J, Valentiner M, Gamborg M, Holm JC
. Adoption of the children's obesity clinic's treatment (TCOCT) protocol into another Danish pediatric obesity treatment clinic. BMC Pediatr. 2015;15:332. (Open Access
).

Summaries:
The TCOCT weight loss program for obese children developed at Holbæk hospital, has systematically been implemented at Hillerød hospital, where it, just as in Holbæk, reduced the degree of childhood obesity with acceptable retention rates.

Vægttabs programmet TCOCT til behandling af overvægtige børn, som er udviklet på Holbæk hospital, er systematisk blevet indført på Hillerød hospital. Hvor det, præcist som i Holbæk, reducerer graden af overvægt med et acceptabelt frafald.

Nielsen LA, Bøjsøe C, Kloppenborg JT, Trier C, Gamborg M, Holm JC. The influence of familial predisposition to cardiovascular complications upon childhood obesity treatment. PLoS One. 2015;10:e0120177.


Summaries:
The study investigated whether familial predispositions for obesity, hypertension, type 2 diabetes, thromboembolic events and/or dyslipidaemia, influenced the level of obesity and the ability to lose weight in a group of obese children receiving treatment for their obesity. We found that children with type 2 diabetes in the family were more obese at the beginning of treatment , and that girls with familial obesity are better at losing weight during treatment.

Dette studie undersøgte om familiær disposition for fedme, forhøjet blodtryk, type 2 diabetes, blodpropper og/eller forhøjet kolesterol, påvirker niveauet af fedme og evnen til at tabe sig i en gruppe af svært overvægtige børn under behandling for deres fedme. Vi fandt, at børn med type 2 diabetes i familien var mere overvægtige ved behandlingens start, og vi fandt, at piger med fedme i familien var bedre til at tabe sig under behandlingen.

Latest update: April 22, 2015



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Located at Frederiksberg Hospital in Copenhagen, the Institute of Preventive Medicine is administratively associated with Bispebjerg Hospital. The Institute of Preventive Medicine is part of the Copenhagen University Hospital, which is an organization for collaboration in research and academic pre- and post-graduate teaching between the Faculty of Health and Medical Sciences at the University of Copenhagen, the hospitals of Region Hovedstaden (the Capital) and the "Region Sjælland."

Institute of Preventive Medicine /
Institut for Sygdomsforebyggelse,
Frederiksberg Hospital
Hovedvejen 5,
Nordre Fasanvej 57
2000 Frederiksberg
Denmark

Tlf: +45 38 16 31 00 (weekdays 8-14)
Fax:+45 38 16 31 19
E-mail: kate.livemore@regionh.dk